A “last resort clinic” (LaRC) in which clinicians and bench scientists around the world collaborate intensively, in some cases remotely, and on a case-by-case basis to help save terminally ill patients, one at a time. This clinic would use the most advanced therapies, some of which are so experimental that they are based on as-yet-unpublished research and are not yet part of any clinical trial. Such therapies do exist, but the LaRC does not. Not yet.

We aim to establish a working group tasked with exploring the possibility of creating a LaRC by conducting applied research on the medical, financial, business, and legal challenges involved in launching and sustaining such an endeavor. The end product of this working group will be a business plan and/or supporting research documentation for a LaRC (or why such a business is not feasible).